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Repositório PUCRS
Browsing by Subject Mycobacterium tuberculosis
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Showing rec. 1 to 20 of 21
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Issue Date
Title
Author(s)
2010
An inorganic complex that inhibits Mycobacterium tuberculosis enoyl reductase as a prototype of a new class of chemotherapeutic agents to treat tuberculosis
Basso, Luiz A.
;
Schneider, Cristopher Z.
;
Santos, Anderson J. A. B. dos
, et al
2021
Anti-tubercular profile of new selenium-menadione conjugates against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain and multidrug-resistant clinical isolates
RIBEIRO, RUAN C.B.
;
DE MARINS, DANIEL B.
;
DI LEO, IRIS
, et al
2014
Biochemical characterization of Mycobacterium tuberculosis IMP dehydrogenase: kinetic mechanism, metal activation and evidence of a cooperative system
ROSTIROLLA, DIANA CAROLINA
;
DE ASSUNÇÃO, THIAGO MILECH
;
BIZARRO, CRISTIANO VALIM
, et al
2013
Biochemical Characterization of Uracil Phosphoribosyltransferase from Mycobacterium tuberculosis
Villela, Anne Drumond
;
Ducati, Rodrigo Gay
;
Rosado, Leonardo Astolfi
, et al
2017
Construction of Mycobacterium tuberculosis cdd knockout and evaluation of invasion and growth in macrophages
Villela, Anne Drumond
;
RODRIGUES-JUNIOR, VALNÊS S
;
PINTO, ANTÔNIO FREDERICO MICHEL
, et al
2021
Design, Synthesis and Antitubercular Activity of 2-(Benzylthio)-1H-benzo[d]imidazoles
RAMBO, RAONÍ
;
WALDOW, ETIENNE
;
ABADDI, BRUNO
, et al
2017
Functional, thermodynamics, structural and biological studies of in silico-identified inhibitors of Mycobacterium tuberculosis enoyl-ACP(CoA) reductase enzyme
MARTINELLI, LEONARDO K. B.
;
ROTTA, MARIANE
;
VILLELA, ANNE D.
, et al
2017
Functional, thermodynamics, structural and biological studies of in silico-identified inhibitors of Mycobacterium tuberculosis enoyl-ACP(CoA) reductase enzyme
MARTINELLI, LEONARDO K. B.
;
ROTTA, MARIANE
;
VILLELA, ANNE D.
, et al
2022
Identification of potential inhibitors of Mycobacterium tuberculosis shikimate kinase: molecular docking, in silico toxicity and in vitro experiments
FREITAS DE FREITAS, TALITA
;
ROTH, CANDIDA DEVES
;
ABBADI, BRUNO LOPES
, et al
2023
Identification of potential inhibitors of Mycobacterium tuberculosis shikimate kinase: molecular docking, in silico toxicity and in vitro experiments
FREITAS DE FREITAS, TALITA
;
ROTH, CANDIDA DEVES
;
ABBADI, BRUNO LOPES
, et al
2018
Is IQG-607 a Potential Metallodrug or Metallopro-Drug With a Defined Molecular Target in Mycobacterium tuberculosis?
ABBADI, BRUNO L.
;
RODRIGUES-JUNIOR, VALNÊS DA SILVA
;
DADDA, ADILIO DA SILVA
, et al
2020
Light-induced disruption of an acyl hydrazone link as a novel strategy for drug release and activation: isoniazid as a proof-of-concept case
NUNES, EDINAIRA DEODATO
;
Villela, Anne Drumond
;
Luiz Augusto Basso
, et al
2015
Mode of Action of Recombinant Hypoxanthine-Guanine Phosphoribosyltransferase from Mycobacterium tuberculosis
PATTA, PAULO CESAR
;
MARTINELLI, LEONARDO KRAS BORGES
;
ROTTA, MARIANE
, et al
2016
Mycobacterium tuberculosis histidinol dehydrogenase: biochemical characterization and inhibition studies
LUNARDI, JULEANE
;
BORGES MARTINELLI, LEONARDO KRAS
;
RAUPP, ALESSANDRA SILVA
, et al
2017
Observed crowding effects on Mycobacterium tuberculosis 2-trans-enoyl-ACP (CoA) reductase enzyme activity are not due to excluded volume only
ROTTA, MARIANE
;
TIMMERS, LUIS F. S. M.
;
SEQUEIROS-BORJA, CARLOS
, et al
2022
Rethinking the MtInhA tertiary and quaternary structure flexibility: a molecular dynamics view
SANTOS CHITOLINA, LUCAS
;
NORBERTO DE SOUZA, OSMAR
;
Luiz Augusto Basso
, et al
2012
Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA)
ROSADO, LEONARDO A
;
CACERES, RAFAEL
;
DE AZEVEDO, WALTER
, et al
2021
Synthesis and Antimycobacterial Activity of 3-Phenyl-1H-indoles
JARDIM ETCHART, RENATA
;
RAMBO, RAONÍ S.
;
LOPES ABBADI, BRUNO
, et al
2022
Synthesis and Antimycobacterial Evaluation of N-(4-(Benzyloxy)benzyl)-4-aminoquinolines
GRAMS, ESTEVÃO SILVEIRA
;
SILVA RAMOS, ALESSANDRO
;
NEVES MUNIZ, MAURO
, et al
2015
Synthesis and Evaluation of Thiazolyl-1H-benzo[d]imidazole Inhibitors of Mycobacterium tuberculosis Inosine Monophosphate Dehydrogenase
KENIA PISSINATE
;
DIANA CAROLINA ROSTIROLLA
;
LAURA MIRANDA PINHEIRO
, et al