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https://hdl.handle.net/10923/1007
Tipo: | article |
Título: | Diclofenac in hyaluronic acid gel: an alternative treatment for actinic cheilitis |
Autor(es): | Lima, Giana da Silveira Silva, Gabriela Ferrari da Gomes, Ana Paula Neutzling Araújo, Lenita Maria Aver Salum, Fernanda Gonçalves |
Editor: | Bauru School of Dentistry |
Fecha de Publicación: | 2010 |
Volumen: | 18 |
Número: | 5 |
Primera página: | 533 |
Última página: | 537 |
Palabras clave: | DICLOFENAC HYALURONIC ACID CHEILITIS ACTINIC RAYS ORAL LEUKOPLAKIA ODONTOLOGIA |
Resumen: | Objective: Actinic cheilitis (AC) is a precancerous lesion of the lip vermillion caused by prolonged exposure to ultraviolet light. The aim of this study was to evaluate the effect of 3% diclofenac in 2.5% hyaluronic acid gel in the treatment of AC. Methods: Thirty-four patients with chronic AC were treated twice a day with topical diclofenac during a period of 30 to 180 days. The individuals were followed up every 15 days by means of clinical examination and digital photographic documentation. Results: Of the 27 patients that completed the study, 12 (44%) showed complete remission of the whitish plaques and exfoliative areas, and 15 (56%) had partial remission of the clinical picture of cheilitis. The latter group was submitted to excision of the leukoplakic areas which diagnosis varied from mild to moderate epithelial dysplasia. Conclusions: The results suggest a promising role for diclofenac in hyaluronic acid gel in the treatment of AC. This treatment has the advantages of not being invasive and showing few side effects. |
URI: | http://hdl.handle.net/10923/1007 |
DOI: | 10.1590/S1678-77572010000500018 |
PMID: | 21085813 |
ISSN: | 1678-7757 |
Aparece en las colecciones: | Artigo de Periódico
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