Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial

LUK, CYNTHIA; CHANG, YEN-HWA; ALVA, AJJAI; CHENG, SUSANNA; SCAGLIOTTI, GIORGIO VITTORIO; FLAIG, THOMAS; TSAI, YU-CHIEH; GEORGOULIAS, VASILEIOS; PARK, INKEUN; GIL, THIERRY; MAVROUDIS, DIMITRIOS; TOPUZOV, MARLEN; GURNEY, HOWARD; RODRIGUEZ-VIDA, ALEJO M.; JANOSKI, JULIANA; CICIN, IRFAN; ALEKSEEV, BORIS; PANG, SEE-TONG; LIPATOV, OLEG; FONT, ALBERT; PEER, AVIVIT; THEODORE, CHRISTINE; GWENAELLE, GRAVIS; DAVIS, IAN; PARK KYONG, HWA; NOMI, HAYAHITO; DE GIORGI, UGO; ANGRA, NATASHA; HE, PHILIP; HASHIMOTO, YASUHIRO; EIGL, BERNHARD J.; ROSA, DIOGO; NECCHI, ANDREA; TAMADA, SATOSHI; LEE, JAE LYUN; JENSEN, NIELS VIGGO; MARTINS, GRAZIELLA; IMKAMP, FLORIAN; SAKAI, HIDEKI; NISHIMURA, KAZUO; JOLY, FLORENCE; VAISHAMPAYAN, ULKA; KIMURA, GO; ALMAGRO, ELENA; POWLES, THOMAS; WILDSMITH, SOPHIE; HASHINE, KATSUYOSHI; KOMYAKOV, BORIS; SUÁREZ, CRISTINA; BÖGEMANN, MARTIN; RIVERA, SAMUEL; SASSA, NAOTO; SRIDHAR, SRIKALA; POMERANTZ, MARK; ARAVANTINOS, GERASIMOS; ZHANG, JINGSONG; CHEVREAU, CHRISTINE; VAN DER HEIJDEN, MICHIEL S.; CASTELLANO, DANIEL; GONZALEZ, JOSE LUIS; BAMIAS, ARISTOTELIS; MIZOKAMI, ATSUSHI; PAVIC, MICHEL; VOORTMAN, JENS; PETRYLAK, DANIEL P.; PLAKSIN, DENIS; EBARA, SHIN; GALSKY, MATTHEW D; OU, YEN-CHUAN; ERMAN, MUSTAFA; DUMEZ, HERLINDE; NARA, TAKETOSHI; ANIDO, URBANO; RODRIGUEZ, JUAN FRANCISCO; NOSOV, ALEXANDER; SMOLIN, ALEXEY; LESNIEWSKI-KMAK, KRZYSZTOF; DURAN, IGNACIO; SRINIVAS, SANDHYA; TOURANI, JEAN-MARC; KEAM, BHUMSUK; NAKAMURA, MOTONOBU; ZALEWSKI, PAWEL; SU, WEN-PIN; KOBAYASHI, TAKASHI; TAMBARO, ROSA; LOPEZ, YAMIL; OKUNO, NORIHIKO; SELLA, AVISHAY; NAKAIGAWA, NOBORU; GUPTA, ASHOK K; NOVIKOV, ANDREY; BERGER, RAANAN; RAVAUX, ANDRE; LOPES, FABIO; MORELLI, FRANCO; GROSS-GOUPIL, MARINE; RETZ, MARGITTA; GRIMM, MARC-OLIVER; FLECHON, AUDE; SUZUKI, HIROYOSHI; CANIL, CHRISTINA; MAZHAR, DANISH; OSANTO, SUSANNE; SHINOHARA, NOBUO; ARRANZ, JOSE ANGEL; MATVEEV, VSEVOLOD; KIM, YU JUNG; DELGADO, IGNACIO; OGAWA, OSAMU; PORTA, CAMILLO; PAPPOT, HELLE; CARTHON, BRADLEY; GIETEMA, JOURIK; ROSENBAUM, ELI; KATER, FABIO; PAPANDREOU, CHRISTOS; PLAS, EUGEN; SUAREZ, CRISTINA; KALOFONOS, HARALAMBOS; ZUCCA, LUIS EDUARDO; SKONECZNA, IWONA; SLOJEWSKI, MARCIN; WESTGEEST, HANS; PONOMAREV, ROMAN; LOIDL, WOLFGANG; KUMAR, SATISH; STATSENKO, GALINA; OBARA, WATARU; KOPYLTSOV, EVGENY; UEMURA, MOTOHIDE; TRAN, ANNA; SOMER, BRADLEY; KISLOV, NIKOLAY; RAMIREZ, FRANCISCO; ALYASOVA, ANNA; UEMURA, HIROJI; FRADET, YVES; DRAKAKI, ALEXANDRA; ENOKIDA, HIDEKI; SHIINA, HIROAKI; GIROTTO, GUSTAVO; MUKHERJEE, SOM D.; SUGIMOTO, MIKIO; GIANNI, LUCA; CULINE, STEPHANE; KAWAKITA, MUTSUSHI; NIEGISCH, GUENTER; HUSSAIN, SYED; ROZANOWSKI, PAWEL; André Poisl Fay; SHIN, SANG JOON; EVANS, LINDA; SIQUEIRA, MARIANA; LYNAM, JAMES; DOMENECH, MONSERRAT; KIKUKAWA, HIROAKI; KREIGER, LAURENCE; PIERSMA, DJURA; POLAKIEWICZ-GILOWSKA, ANNA; MACFARLANE, ROBYN; FERREIRA CASTRO, ANA; HAMZAJ, ALKETA; LEE, JAE-LYUN; SUZUKI, AKITAKA; LORIOT, YOHANN; TSIATAS, MARINOS; JONES, ROBERT; FRANKE, FABIO; YONESE, JUNJI; AGERBAEK, MADS; NORTH, SCOTT; SU, YU-LI; KARYAKIN, OLEG; KURI, ROBERTO; BENDELL, JOHANNA; MACEDO, ELEAZAR; VAN DER HEIJDEN, MICHIEL S; DETTINO, ALDO; CHOWDHURY, SIMON; PETRYLAK, DANIEL P; FINCH, DAYGEN; YAMAGUCHI, AKITO; ZAUCHA, RENATA; FERNANDES, ISABEL; HATIBOGLU, GENCAY; FAY, ANDRÉ P.; HOCKING, CHRISTOPHER; AARTS, MAUREEN; MUKHERJEE, SOM D; LEVIN, WENDY; GALSKY, MATTHEW D.; YOSHIMURA, KAZUHIRO; KALEBASTY, ARASH REZAZADEH; WIECHNO, PAWEL; SHARIAT, SHAHROKH; PÉREZ-VALDERRAMA, BEGOÑA; BORGES, GIULIANO; ROSALES, JOSEPH; CRABB, SIMON; SAUTOIS, BRIEUC; TOKUDA, NORIAKI; ARAI, GAKU; VILLALOBOS PRIETO, ALBERTO; TAGAWA, SCOTT; MULDER, SASJA; PARK, SE HOON; VAZQUEZ, FEDERICO JOSE; VASUDEV, NAVEEN; EIGL, BERNHARD J; FRANK, STEPHEN; SENGELOV, LISA; BELLMUNT, JOAQUIM; ALIMOHAMED, NIMIRA

Utilize este identificador para citar ou criar um atalho para este documento: https://hdl.handle.net/10923/17882

Tipo:	Article
Título:	Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial
Autor(es):	VAN DER HEIJDEN, MICHIEL S GALSKY, MATTHEW D PETRYLAK, DANIEL P OGAWA, OSAMU PARK, SE HOON LEE, JAE-LYUN EIGL, BERNHARD J MUKHERJEE, SOM D SUÁREZ, CRISTINA André Poisl Fay DURAN, IGNACIO WILDSMITH, SOPHIE HE, PHILIP ANGRA, NATASHA GUPTA, ASHOK K LEVIN, WENDY BELLMUNT, JOAQUIM VAN DER HEIJDEN, MICHIEL S. NECCHI, ANDREA CASTELLANO, DANIEL BAMIAS, ARISTOTELIS LEE, JAE LYUN DE GIORGI, UGO BÖGEMANN, MARTIN EIGL, BERNHARD J. TSIATAS, MARINOS POWLES, THOMAS NOVIKOV, ANDREY SKONECZNA, IWONA MUKHERJEE, SOM D. SUAREZ, CRISTINA WESTGEEST, HANS FRADET, YVES FLECHON, AUDE OU, YEN-CHUAN PARK, INKEUN MATVEEV, VSEVOLOD PÉREZ-VALDERRAMA, BEGOÑA CHENG, SUSANNA FRANK, STEPHEN GURNEY, HOWARD ANIDO, URBANO HAMZAJ, ALKETA RETZ, MARGITTA SRIDHAR, SRIKALA SCAGLIOTTI, GIORGIO VITTORIO VOORTMAN, JENS ALEKSEEV, BORIS ALYASOVA, ANNA KOMYAKOV, BORIS DUMEZ, HERLINDE PAVIC, MICHEL KIMURA, GO MIZOKAMI, ATSUSHI OSANTO, SUSANNE ARRANZ, JOSE ANGEL PIERSMA, DJURA SHIN, SANG JOON KARYAKIN, OLEG DELGADO, IGNACIO GONZALEZ, JOSE LUIS PANG, SEE-TONG TRAN, ANNA LIPATOV, OLEG SU, WEN-PIN FLAIG, THOMAS ALVA, AJJAI PARK KYONG, HWA KOPYLTSOV, EVGENY ALMAGRO, ELENA DOMENECH, MONSERRAT CHANG, YEN-HWA SAUTOIS, BRIEUC RAVAUX, ANDRE ARAVANTINOS, GERASIMOS GEORGOULIAS, VASILEIOS MULDER, SASJA KIM, YU JUNG KATER, FABIO CHEVREAU, CHRISTINE TAGAWA, SCOTT ZALEWSKI, PAWEL JOLY, FLORENCE LORIOT, YOHANN HATIBOGLU, GENCAY GIANNI, LUCA MORELLI, FRANCO TAMBARO, ROSA HASHIMOTO, YASUHIRO NOSOV, ALEXANDER FONT, ALBERT RODRIGUEZ-VIDA, ALEJO M. JONES, ROBERT VASUDEV, NAVEEN SRINIVAS, SANDHYA ZHANG, JINGSONG GIL, THIERRY FINCH, DAYGEN GRIMM, MARC-OLIVER SU, YU-LI CHOWDHURY, SIMON HOCKING, CHRISTOPHER PLAS, EUGEN NORTH, SCOTT JENSEN, NIELS VIGGO THEODORE, CHRISTINE IMKAMP, FLORIAN PEER, AVIVIT KOBAYASHI, TAKASHI SAKAI, HIDEKI SASSA, NAOTO YOSHIMURA, KAZUHIRO AARTS, MAUREEN FERREIRA CASTRO, ANA TOPUZOV, MARLEN RODRIGUEZ, JUAN FRANCISCO VAZQUEZ, FEDERICO JOSE TSAI, YU-CHIEH CRABB, SIMON HUSSAIN, SYED BENDELL, JOHANNA GROSS-GOUPIL, MARINE GWENAELLE, GRAVIS BERGER, RAANAN STATSENKO, GALINA EVANS, LINDA DRAKAKI, ALEXANDRA SOMER, BRADLEY DAVIS, IAN LYNAM, JAMES BORGES, GIULIANO DETTINO, ALDO FAY, ANDRÉ P. MARTINS, GRAZIELLA ZUCCA, LUIS EDUARDO AGERBAEK, MADS KALOFONOS, HARALAMBOS ROSENBAUM, ELI ENOKIDA, HIDEKI KIKUKAWA, HIROAKI NISHIMURA, KAZUO TAMADA, SATOSHI UEMURA, MOTOHIDE LOPEZ, YAMIL GIETEMA, JOURIK SLOJEWSKI, MARCIN FERNANDES, ISABEL SMOLIN, ALEXEY MAZHAR, DANISH KALEBASTY, ARASH REZAZADEH CARTHON, BRADLEY LOIDL, WOLFGANG FRANKE, FABIO GIROTTO, GUSTAVO ALIMOHAMED, NIMIRA MACFARLANE, ROBYN PAPPOT, HELLE NIEGISCH, GUENTER MAVROUDIS, DIMITRIOS SELLA, AVISHAY PORTA, CAMILLO EBARA, SHIN NAKAMURA, MOTONOBU OBARA, WATARU OKUNO, NORIHIKO SHINOHARA, NOBUO SUGIMOTO, MIKIO SUZUKI, AKITAKA TOKUDA, NORIAKI UEMURA, HIROJI YAMAGUCHI, AKITO RAMIREZ, FRANCISCO ROZANOWSKI, PAWEL WIECHNO, PAWEL KEAM, BHUMSUK KISLOV, NIKOLAY PLAKSIN, DENIS CICIN, IRFAN KUMAR, SATISH GALSKY, MATTHEW D. PETRYLAK, DANIEL P. ROSALES, JOSEPH VAISHAMPAYAN, ULKA CULINE, STEPHANE PAPANDREOU, CHRISTOS NARA, TAKETOSHI ERMAN, MUSTAFA KREIGER, LAURENCE JANOSKI, JULIANA ROSA, DIOGO SIQUEIRA, MARIANA CANIL, CHRISTINA SENGELOV, LISA TOURANI, JEAN-MARC ARAI, GAKU HASHINE, KATSUYOSHI KAWAKITA, MUTSUSHI NAKAIGAWA, NOBORU NOMI, HAYAHITO SHIINA, HIROAKI SUZUKI, HIROYOSHI YONESE, JUNJI KURI, ROBERTO MACEDO, ELEAZAR RIVERA, SAMUEL VILLALOBOS PRIETO, ALBERTO POLAKIEWICZ-GILOWSKA, ANNA ZAUCHA, RENATA LOPES, FABIO PONOMAREV, ROMAN POMERANTZ, MARK SHARIAT, SHAHROKH LUK, CYNTHIA LESNIEWSKI-KMAK, KRZYSZTOF
In:	LANCET ONCOLOGY
Data de Publicação:	2020
Volume:	21
Número:	12
Página Inicial:	1574
Página Final:	1588
URI:	https://hdl.handle.net/10923/17882
DOI:	DOI:10.1016/S1470-2045(20)30541-6
ISSN:	1470-2045
Aparece nas Coleções:	Artigo de Periódico

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